In 440 BC the historian Herodotus observed Scythians using cannabis ritualistically, around the time Greek playwrights Aristophanes and Orestes wrote about the Eleusinian mysteries in their plays.
"The Frogs by Aristophanes (405 B.C.E.) involves the sybaritic Dionysus as the new god of Eleusis. Some scholars think the play focuses on the exiled general Alcibiades, who stole the Eleusinian sacrament kykeon from the temple of the grain goddess Demeter, and started partying with it at orgies at his home....." (excerpted from Tokin' Women: A 4000-Year Herstory).
Marcus Tullius Cicero, the Roman orator who gave us the enduring maxim, “Let the punishment fit the crime” wrote:
For it appears to me that among the many exceptional and divine things your Athens has produced and contributed to human life, nothing is better than those [Eleusinian] mysteries. For by means of them we have transformed from a rough and savage way of life to the state of humanity, and have been civilized.”
Nonetheless, in 392 AD, the Romans outlawed the Mysteries.