From my youthful TV watching, I seem to recall Morticia (Carolyn Jones) and Gomez (John Astin) of "The Addams Family" (1964-66) smoking regularly from a Turkish hookah. One researcher claims the hookah was scrubbed from later re-runs, but someone's made an animated GIF of the puffing pair, and this clip has survived:
Based on a series of New Yorker cartoons by Charles Addams that debuted in 1938, the TV series is enduringly popular in reruns; an animated series (starting with an appearance on Scooby Doo in 1972) followed, as did two films and a musical.
Despite being offbeat and morbid, the Addams Family were loving and accepting. Just like pot smokers.
A hookah also appeared regularly on the TV series Bewitched from the same era, smoked by Endora and Dr. Bombay.